By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. This should pass after a few days. Isosorbide mononitrate (Monoket) is good for a specific type of chest pain (called angina), but it can cause headaches or dizziness after you take it. However, you should not flush this medication down the toilet. include protected health information. People with kidney problems should be able to take the usual dose of isosorbide mononitrate (Monoket). Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. Do not store in the bathroom. Accessed Sept. 7, 2022. In: Current Medical Diagnosis & Treatment 2022. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). This is called a medicine interaction. Egton Medical Information Systems Limited. Making any changes without doctor's advice can be dangerous. 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (in Cafergot, in Migergot), methylergonovine (Methergine), methysergide (Sansert; no longer available in the U.S.), and pergolide (Permax; no longer available in the U.S.); medications for high blood pressure, heart failure, or an irregular heartbeat. It will not treat an angina attack that has already begun. Consult your pharmacist or local waste disposal company. There are 195 drugs known to interact with Isosorbide mononitrate (Monoket) is a nitrate vasodilator. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. privacy practices. you should know that isosorbide may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, or at any time, especially if you have been drinking alcoholic beverages. Clipboard, Search History, and several other advanced features are temporarily unavailable. There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Higher dosages are associated with stomach irritation and Which drugs or supplements interact with isosorbide mononitrate? This branded product is no longer on the market. Yes, it's good for health but don't take it excesse in amount, use once daily for 1 month then stop it or take once a weekly. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. It does not work fast enough to relieve the pain of an angina attack that has already started. Isosorbide controls chest pain but does not cure coronary artery disease. May also be prescribed off label for Esophageal Spasm. Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma Side effects : headache, mild dizziness It works and leaves the body quickly, so it needs to be taken twice a day. Do not change the dosing times unless directed by your doctor. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. Bethesda, MD 20894, Web Policies It works by . Methods: I strongly feel that there is coronary ischemia. These side effects may go away during treatment as your body adjusts to the medicine. This survey is being conducted by the WebMD marketing sciences department. This medicine is available only with your doctor's prescription. Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. The information on this page is written and peer reviewed by qualified clinicians. Drug information provided by: IBM Micromedex. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Isosorbide mononitrate helps to prevent angina chest pain from developing. Isosorbide dinitrate dose 30-120 mg daily in divided doses. It can make you really dizzy. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. What special precautions should I follow? Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Isosorbide Mononitrate side effects by likelihood and severity. Store it at room temperature and away from excess heat and moisture (not in the bathroom). St. John's wort. The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. You will find a full list in the manufacturer's information leaflet supplied with your medicine. In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). Diabetes treatment: Can cinnamon lower blood sugar? Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. You can take your doses either before or after meals. My cardiologist recommended I get on metropolol. It might help to take isosorbide mononitrate and dinitrate after meals. Although not all of these side effects may occur, if they do occur they may need medical attention. It works to relax your blood vessels. Generic alternatives may be available. isosorbide mononitrate, along with Never give it to other people even if their condition appears to be the same as yours. On the other hand, the ER version can only help prevent angina. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Moderately clinically significant. Licorice. If you notice other effects not listed above, contact your doctor or pharmacist. Alternative drugs to the conditions Isosorbide mononitrate treats: Angina High blood pressure Stable angina Chest pain Heart disease Heart attack Angina unstable Heart disease congenital Coronary heart disease Heart failure Pulse Heart rate irregular Coronary artery spasm Angioplasty amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. Disclaimer. All rights reserved. Do not share this medication with others. 7 disease interactions. What are the side effects of Isosorbide Mononitrate ? Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). If you have recently had a head injury or a heart attack. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. It might help to keep the room cool and use a fan. Avoid combinations; the risk of the interaction outweighs the benefit. Be sure to mention any of the following: aspirin; beta blockers such as atenolol (Tenormin, Tenoretic), carteolol , labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, in Dutoprol, in Lopressor HCT), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), sotalol (Betapace, Sorine, Sotylize), and timolol; calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), diltiazem (Cardizem, Cartia, Dilt-CD, others), felodipine (Plendil), isradipine, nifedipine (Adalat CC, Afeditab, Procardia), and verapamil (Calan, Covera, Verelan); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. information and will only use or disclose that information as set forth in our notice of Treatment and prognosis of heart failure with preserved ejection . Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. tell your doctor and pharmacist if you are allergic to isosorbide; nitroglycerin tablets, patches, or ointment; any other medications, or any of the ingredients in isosorbide tablets, extended-release tablets, or extended-release capsules. View more, Nitroglycerin dilates veins, relieving chest pain and lowering blood pressure. Contact your provider right away if you feel as if you are going to pass out and are experiencing an irregular heartbeat, nausea, vomiting, changes in vision, more sweating, or cold and clammy skin. Isosorbide-2,5-dinitrate and isosorbide-5-mononitrate, the low-potent organic nitrates, are directly metabolized in the endoplasmic reticulum of the vascular smooth muscle cells via cytochrome P450 enzymes, resulting in direct production of nitric oxide (Mnzel et al., 2005).In contrast, the highly potent organic nitrates such as glyceryl trinitrate (GTN) and pentaerythritile tetranitrate . When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Do not keep out-of-date or unwanted medicines. Try our Symptom Checker Got any other symptoms? St. Joseph 81 mg Aspirin Enteric Safety-Coated. . Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. See also: aspirin side effects in more detail. In Canada - Call your doctor for medical advice about side effects. Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. Instead, the best way to dispose of your medication is through a medicine take-back program. But only about 25% of people who take herbal supplements tell their health care providers. During pregnancy, this medication should be used only when clearly needed. Cardizem may also be used for purposes not listed in this medication guide. PMC It works more slowly and lasts for about 12 hours, so you only need to take it once a day. Natural Medicines. Things to remember when you fill your prescription. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks ( chest pain ). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Be sure to follow your provider's instructions about when to take isosorbide mononitrate (Monoket). other information we have about you. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Prescribed for Angina, Anal Fissure and If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Stopping isosorbide mononitrate (Monoket) suddenly can cause you to have a worsening of your chest pain. coma (loss of consciousness for a period of time). A randomized, double-blind, cross-over study. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Along with its needed effects, a medicine may cause some unwanted effects. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). If you have an underactive thyroid gland. Available for Android and iOS devices. Thirty percent of the patients never experienced headache from the given dosages. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. https://naturalmedicines.therapeuticresearch.com. This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way. Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)? The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. Let your provider know if they are excessive. An official website of the United States government. All rights reserved. The .gov means its official. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. This information is aggregated and used to produce personalized reports that patients can reference. Results: Danshen. https://naturalmedicines.therapeuticresearch.com. Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. All rights reserved. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. If concomitant therapy cannot be avoided, monitor clinical effects of the . Accessed Sept. 7, 2022. Limit alcoholic beverages. Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. 55 ratings on Drugs.com. Store in a cool, dry place, away from direct heat and light. I took this for 4 days, and my headaches were unbearable. Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. The body tends to develop a tolerance (decreased sensitivity) to ISMN when it is used continuously over 24 hours. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. [2] Longer-acting tablets and capsules are taken once daily in the morning. Saper RB. Take the missed dose as soon as you remember it. You can consult me online for homeopathic treatment. It can cause your blood pressure to become dangerously low. American Society of Health-System Pharmacists, Inc. Disclaimer, U.S. Department of Health and Human Services. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. Copyright, 2023. Isosorbide mononitrate systemic 60 mg (A ID). Patient is a UK registered trade mark. Otherwise, call a poison control center right away. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. To view a report comparing 3 (or more) medications, please sign in or create an account. Do not stop taking it without consulting your doctor. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). Make sure laboratory personnel and all your doctors know you use this drug. The authors assessed the occurrence of angina pectoris and headache by diary cards while taking into account the number of isosorbide dinitrate sublingual puffs and paracetamole tablets required. Some people feel dizzy or fall when changing positions, such as going from sitting to standing. This document does not contain all possible drug interactions. Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
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